Bats may be the source of a new Sars-like virus which killed a man in Saudi Arabia, according to an analysis of the coronavirus' genome. Two other people have been infected and one, who was flown to the UK for treatment in September, is still in intensive care. Experts, writing in the journal mBio, said the virus was closely related to other viruses in bats. It is thought the virus does not pass readily from one person to another.
Coronaviruses
are a family of viruses ranging from the common cold to the Sars (severe acute
respiratory syndrome) virus. They infect a wide range of animals.
In
2002 an outbreak of the Sars coronavirus killed about 800 people after it
spread from Hong Kong to more than 30 countries around the world.
Genetic
code
The
new coronavirus was detected after a 60-year-old man died of pneumonia and
kidney failure in Saudi Arabia in June. A second man, who was brought to the UK
from Qatar, still needs an artificial lung to stay alive.The UK's Health
Protection Agency (HPA published the full genetic sequence of the case in London) earlier this month.
Dr
Ron Fouchier, from the Erasmus Medical Centre in the Netherlands, analysed the
case from Saudi Arabia. He said both cases were related, but it looked as
though the men had been infected separately from animals rather than the virus
being passed between people. "The virus is most closely related to viruses
in bats found in Asia, and there are no human viruses closely related to it
therefore, we speculate that it comes from an animal source."
Prof
Maria Zambon, the director of the HPA's reference microbiology services, said
bats were a natural reservoir of coronavirus: "There's some in cats and in
humans, but the broadest range is found in bats." However, she said it was
not "definitively" from bats as the virus could have spread to another
animal first, which then passed the virus onto humans. Researchers are trying to determine if the
virus will be a "dead end" infection which can spread only from
animal to person, like rabies, or will be able to spread from one person to
another like HIV after it made the jump from primates. Prof Zambon said there
were "fairly strong steers" that it would be a dead end. Health care
workers who came into contact with the patients "don't seem to be
ill" but full blood test results are still needed, she said.
Source: BBC News
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