Parkinson’s disease has long been
a difficult disease to diagnose accurately. Typically patients who are thought
to have the disease are treated with medication. If the medication is effective
in treating the symptoms of the disease, they are then thought to have it.
However, all of that may change —
if new research is confirmed by others. Researchers at Michigan State
University have identified a new, non-invasive way to diagnose Parkinson’s
disease that they say has proven to be effective more than 90 percent of the
time. This new method also has the potential to track the progression of the
disease, as well as measure the effectiveness of treatments.
Parkinson’s disease is a
neurological disorder affecting a half million people in the United States,
with 50,000 newly diagnosed cases every year. It occurs when nerve cells in the
brain stop producing the neurotransmitter dopamine, which helps control muscle
movement. Without dopamine, the nerve cells cannot properly send messages,
leading to the loss of muscle function. The new technique involves monitoring a
patient’s speech patterns, specifically, movement patterns of the tongue and
jaw. “In Parkinson’s disease, a common limitation is that the movements become
slow and have a reduced range,” said Rahul Shrivastav, Ph.D., professor at
Michigan State University and a member of the team developing the new method.
“We believe we see this pattern in speech too — the tongue doesn’t move as far
as it should, doesn’t move as quickly as it should and produces subtle changes
in speech patterns.”
This method is particularly
sensitive to Parkinson’s disease speech, said the researchers, who believe it
can be effective in analyzing speech in just 2 seconds. “That’s significant in
several ways: The detection methodology is noninvasive, easy to administer,
inexpensive and capable of being used remotely and in telemedicine
applications,” he said. Presently, there are no tried-and-true methods for
diagnosing Parkinson’s, according to Shrivastav, who said that if a person is
showing early symptoms of the disease, which include tremors, slower movements
or rigid muscles, he or she is given a drug to treat the disease. “If the
symptoms go away, then it’s assumed you must have Parkinson’s disease,” he
said.
In more advanced cases, symptoms
are usually prominent enough that it is fairly easy to diagnose, he added. While
there is no cure for Parkinson’s disease, early detection is particularly
important since the treatments currently available for controlling symptoms are
most effective at that stage, according to the researchers. Rahul Shrivastav,
Ph.D. is a professor and chairperson of Michigan State University’s Department
of Communicative Sciences and Disorders.
Source: Psych Central
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