Exposure to a household chemical in the womb may increase children's
risk of eczema, a new study suggests.
In the study, mothers who were exposed to high concentrations of a
chemical called butylbenzyl phthalate when they were pregnant were 52 percent
more likely to have children who developed eczema by age 2, compared with
mothers who were exposed to lower concentrations of the chemical, the study
found. Eczema is a chronic skin disorder that causes dry, itchy red skin on the
face, scalp, or extremities. It can be brought on by a hypersensitive reaction,
similar to allergies, according to the National Institutes of Health.
Butylbenzyl phthalate, or BBzP, is found vinyl flooring, artificial
leather and other materials, and can be can be slowly released into the air in
homes. Urine tests showed that all but one woman in the study had at least some
exposure to the chemical.
The study found an association, not a cause-effect link between BBzP and
excema, and future studies should look at whether reducing exposure to the
compound leads to a reduction in risk of eczema, the researchers said. The
study also showed that exposure to BBzP was not associated with an increased
risk of allergies to cockroaches, dust mites or mice, the researchers said.
Dr. Rachel Miller, of the Columbia Center for Children's Environmental
Health, and colleagues analyzed information from 407 nonsmoking
African-American and Dominican women and their children in New York City. The
researchers measured the concentration of BBzB in the urine of the women during
their third trimester of pregnancy. Following birth, the mothers were asked if
their child had been diagnosed with eczema.
A total of 113 children, or 30 percent, had eczema by age two, and the
condition was more common among African-American children in the study than
Dominican children. The higher the concentration of BBzP in a woman's urine
during pregnancy, the more likely it was that her child developed eczema. The
researchers noted that they did not measure exposure to BBzP after birth, which
could influence the results, and that the presence of eczema was self-reported,
and not confirmed by a doctor.
The study was published online June 26 in the journal Environmental
Health Perspectives.
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