- Denosumab recommended as option for adults with advanced breast cancer
- Nice says it's also for those with other tumours that have spread to the bone
- But it's not for prostate cancer patients, who normally receive other drugs
- Helps to avoid complications such as bone fractures and spinal compression
A new drug to prevent
the crippling effects of cancer spreading to the bone has received the final
green light making it available to NHS patients.
Denosumab, marketed as
Xgeva, helps patients avoid complications such as bone fractures and spinal
compression - when the spinal cord is painfully squeezed by the bone. The
National Institute for Health and Clinical Excellence (Nice), which assesses
the cost effectiveness of new treatments, today (Oct. 24) published its final
guidance on the drug.
It recommended
denosumab as a treatment option for adults with advanced breast cancer and
other tumours that have spread to the bone, other than prostate cancer. Prostate cancer
patients are normally prescribed other drugs called bisphosphonates to prevent
bone complications.
If there are medical
reasons why they cannot take bisphononates, they will also qualify for
denosumab under the new guidance.
Preventative measure:
Denosumab, marketed as Xgeva, helps patients avoid complications such as bone
fractures and spinal compression - when the spinal cord is painfully squeezed
by the bone (file picture)
'Denosumab is a welcome addition to the current
treatment options available for the people in whom it has been shown to be
clinically and cost effective'
Professor Carole
Longson, Nice
Professor Carole
Longson, director of the centre for health technology evaluation at Nice, has
praised the new drug. She said: ‘Denosumab is a welcome addition to the current
treatment options available for the people in whom it has been shown to be
clinically and cost effective.’ Draft guidance on the drug was issued by Nice
in August. With the final guidance, the NHS in England and Wales now has a
legal obligation to begin funding treatment with denosumab.
Daily Mail UK
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