All those hours Americans spend in their office chairs or on their sofas
may be packing on a particularly unhealthy form of fat around the heart, a new
study suggests. What’s more, the fat stayed in place even when people undertook
regular exercise, according to a study reported this week in Los Angeles at the
annual meeting of the American Heart Association.
CT scans of more than 500 older Americans found that excess time spent
sitting “was significantly related to pericardial fat around your heart,” said
study lead author Britta Larsen, a postdoctoral researcher in the department of
cardiovascular epidemiology at the University of California, San Diego. There
have been numerous large studies recently suggesting that when it comes to its
deleterious health effects, sitting is not just the absence of physical
activity — it has effects on the body that go beyond lack of exercise.
According to Larsen, that means that “even if you run every day but then
you sit for eight hours a day, the sitting is still doing something bad for
your health.” She also noted that studies have found sitting to be detrimental
to health even after scientists factored out excess weight gain. “So, we wanted
to see if sitting was related to the distribution of fat, because
different types of fat are worse than others,” Larsen said. The study looked at
data on 504 Californian adults, average age 65. In particular, Larsen’s team
examined CT scan data that showed how much of certain types of body fat were
deposited in each participant’s body. “We looked at subcutaneous fat, which is
stuff on the outside [for example, a "pot belly"]; then visceral fat,
which is around your organs; intramuscular fat, which is actually in your
muscles; intrathoracic [chest cavity] fat; and pericardial fat, which is around
your heart,” Larsen said.
The participants were also asked about the amount of time per week they
spent sitting and how much time they had spent being physically active. The
study found that the more time spent sitting, the bigger the area of fat
deposited around a person’s heart, Larsen said. She explained that pericardial
fat “is strongly related to cardiovascular disease. It gets in the way of heart
function, it clogs up your arteries — you don’t want it there.”
Prolonged sitting was not significantly related to any of the other
types of fat, the study found. There was also bad news for people who sit a lot
but assume that they can exercise away all that pericardial fat. According to
the study, regular exercise was not related to a lessening of
pericardial fat, although it did help reduce visceral fat around the organs,
which is strongly tied to diabetes and metabolic disease. All of this means
that for people who want to prevent the buildup of unhealthy fat deposits,
exercise may not be enough.
The study “really emphasizes that [sitting and exercise] are two
distinct behaviors,” Larsen explained. “In order to really be healthy you need
to focus on both — get enough exercise but also not sit for 10 hours per day
like most of us do.” She agreed that is probably a tall order for millions of
office-bound Americans. Still, simple innovations, such as “standing desks,” or
getting up for a stroll every hour or two at work can help mitigate sitting’s
effects. “Sitting really is bad for your heart,” Larsen said. “So we are hoping
that the workplace, especially, becomes more standup-friendly.”
One expert said the study raises interesting issues, but it’s too early
to link sitting with heart disease and heart attack. “Other studies have
indicated that pericardial fat is associated with cholesterol blockages,
particularly in people who are less obese,” noted Dr. Stephen Green, associate
chairman in the department of cardiology at North Shore University Hospital in
Manhasset, N.Y. However, he added, “in this study there was no direct linkage
between sitting and heart attacks, or sitting and cholesterol blockages.”
Study author Larsen also stressed that the study could only point to an
association between sitting and pericardial fat, it could not prove a
cause-and-effect relationship. Dr. Sripal Bangalore, an assistant professor of
medicine at NYU School of Medicine in New York City, added that the study may
help unravel the mystery of why a “couch potato” lifestyle is so unhealthy. “The
current study shows that a sedentary lifestyle may have a differential increase
in fat accumulation based on activity level,” he said. “It is very intriguing
and should be confirmed in future studies,” Bangalore added. “I guess until
that time, it is time to sit less and be more active,” said Bangalore, who is
also director of research at the Cardiovascular Outcomes Group at NYU Langone
Medical Center. Findings presented at medical meetings are typically considered preliminary
until published in a peer-reviewed journal.
Source: News.health
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