When George Orwell wrote in his classic novel Animal Farm that man and
pig are almost identical he was closer to the truth than he realised, according
to a new study.
Scientists have undertaken the largest ever study of the pig genome have
found that swine are adaptable, easy to seduce with food and susceptible to
domestication - much like humans. The findings, published in the journal
Nature, also show that pigs suffer from the same genetic and protein
malfunctions that account for many human diseases, including Alzheimer’s,
Parkinson’s and obesity.
A Duroc pig (left) and their ancestor-like cousin, a wild boar (right) as a new genetic study reveals much about their evolutionary history, sensory perceptions and similarity to humans.
With further study, a swine’s gene’s could unlock new treatments to
combat these devastating illnesses, researchers said. Professor Martien Groenen,
a principal investigator on the study, said: 'We identified many more gene
variants implicated in human disease, further supporting the pig as a valuable
biomedical model.'
ANIMAL FARM
According to Orwell, the book reflects events leading up to and during the Stalin era before the Second World War.
In his essay of 1946, Why I Write, he wrote that Animal Farm was the first book in which he had tried, with full consciousness of what he was doing, 'to fuse political purpose and artistic purpose into one whole.'
The study also unlocked some of the secrets behind how humans first
domesticated pigs and farmed them for food.
The ancestor of the modern domestic
pig first emerged in Southeast Asia and gradually migrated across Eurasia. But
while truffle-hunting pigs are well known for their keen sense of smell, which
allow them to sniff out the expensive delicacy, it might have been their poor
sense of taste that first attracted humans to them. Pigs have far fewer bitter
taste receptor genes than humans, and their perception of sweet and meaty
flavours is also radically different, researchers said.
Alan Archibald, a professor at the University of Edinburgh and a
principal investigator on the study, said: 'Understanding the genes that shape
the characteristics of pigs can point to how and why they were domesticated by
humans. 'Perhaps it was their ability to eat stuff that is unpalatable to us
humans. This understanding of the genetic origins of modern pigs is important
as we breed pigs to meet growing demand more efficiently and to resist old and
emerging diseases.' Scientists in Scotland, America and the Netherlands
conducted the groundbreaking study - the most thorough genome analysis ever of
the domestic pig and its wild boar counterparts.
Their findings have important implications for agriculture as more than
a billion pigs are farmed around the world each year. Unlike the domestic cow,
whose ancestors are now extinct, pigs still have distant relations living in
the wild. Farmers could use genes still found in wild boar to better breed
domestic pigs today, researchers said. Bob Easter, one of the study’s authors,
said: 'This study demonstrates the benefits of basic genomic research on
agricultural animals and their closest living relatives. 'This work has
important implications for agriculture, contributes to our understanding of
evolution and will aid in human medicine.'
Source: Daily Mail UK
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