Scientists are reporting the first identification of a chemical basis for people’s preference for certain brands of vodka. |
Drunks are prone to injury, be it from a rooftop fall,
a barroom fight or an oversight while juggling. But new research suggests that
once an injury has occurred, the same substance that leads drinkers to folly
may help save them from its consequences. The results of a study from the
University of Illinois at Chicago (UIC) show that not only does an appreciable blood-alcohol level seem to increase a trauma victim's chances of survival after being
admitted to a hospital, but that the drunker a victim is, the more likely he or
she is to survive. "After an injury, if you are intoxicated there seems to
be a pretty substantial protective effect," said Lee Friedman, the author
of the study and an assistant professor of environmental and occupational
health sciences at UIC, in a statement issued by the school. "The
more alcohol you have in your system, the more the protective effect."
Friedman's study shows a correlation between a high
blood-alcohol content and an increased chance of survival after a serious
injury, but it doesn't necessarily demonstrate that alcohol is the root cause
of the increase. While previous studies have examined the interactions between
trauma outcome and blood-alcohol content, most have focused either on
particular injuries, such as head trauma, or particular injury mechanisms, such as car accidents.
Friedman analyzed all 190,612 patients treated at
Illinois' trauma centers between 1995 and 2009 who were tested for
blood-alcohol content, with levels ranging from zero to 0.5 percent at time of
admission. (Blood-alcohol levels above about 0.35 percent can be fatal.) He
found that with the exception of burn injuries, the mortality rates of all
types of traumatic injury decreased as the blood-alcohol content of victims
rose.
At the upper bounds of intoxication, mortality rates
were cut by nearly 50 percent, said Friedman. The effect, however, was not
equally strong for all types of trauma, with victims of penetrating injuries,
such as gunshot and stab wounds, seeming to show the greatest benefit from alcohol. Friedman broke his data into subgroups, classified by
severity and type of injury, before drawing any conclusions, to account for the
possibility that drinkers suffer a disproportionate amount of relatively minor
traumatic injuries.
There is a folk belief that drunken injuries,
especially those incurred during car crashes, are likely to be less severe, due
perhaps to increased relaxation or limpness at the time of an accident. But
Friedman says his research has convinced him that this belief is "probably
grossly overestimated and false." His findings don't show that a drunk
driver's injuries during a car crash are likely to be less serious than those
suffered by potential sober victims, just that if all parties suffer the same
injuries, the sober ones are more likely to die. "You don't die from the
injury itself, you die from the subsequent physiological response, things like
inflammation and rapid fluid loss," Friedman told Life's Little Mysteries.
"If you get shot by a gun, it's not the hole that kills you."
And it's when a person's body goes into emergency
preservation mode — tripping a cascade of physiological panic buttons that can
ironically end in death — that alcohol seems to help most. Friedman is
conducting a follow-up study that looks at the relation between blood-alcohol content and the likelihood of complications that often result from traumatic
injury, such as heart and kidney failure. His preliminary data suggests alcohol
combats both of those outcomes, and this, he says, is consistent with the boost
alcohol gives to myocardial contractility, or the heart's ability to pump
blood. Friedman's study notes that if drunken trauma victims are more likely to
die before being hospitalized than their sober counterparts, his data sample
may be biased.
Source: Live Science
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